Overview

Zestril 10mg Tablet is a widely used medication primarily prescribed to treat high blood pressure (hypertension) and heart-related conditions. It belongs to a class of drugs known as angiotensin-converting enzyme (ACE) inhibitors, which help relax blood vessels, improving blood flow and reducing strain on the heart.

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Composition and Mechanism of Action

Each Zestril 10mg Tablet contains Lisinopril as the active ingredient. Lisinopril works by blocking the action of ACE, an enzyme responsible for producing angiotensin II, a substance that narrows blood vessels. By inhibiting this enzyme, Zestril helps lower blood pressure, enhance blood circulation, and reduce the risk of cardiovascular diseases.

Indications – Who Should Use Zestril 10mg Tablet?

Zestril 10mg Tablet is prescribed for the following conditions:

Hypertension (High Blood Pressure): Helps lower blood pressure, reducing the risk of stroke, heart attack, and kidney problems.
Heart Failure: Improves heart function and prevents complications associated with heart failure.
Post-Heart Attack Treatment: Reduces the risk of further heart complications following a myocardial infarction.
Diabetic Nephropathy (Kidney Disease in Diabetics): Helps protect kidney function in patients with diabetes.

Benefits of Zestril 10mg Tablet

Effective Blood Pressure Control: Lowers and stabilizes blood pressure, preventing long-term complications.
Heart Protection: Reduces strain on the heart, improving heart function.
Kidney Protection in Diabetics: Slows the progression of kidney disease in diabetic patients.
Stroke Prevention: Lowers the risk of strokes in hypertensive patients.

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Dosage and Administration

Recommended Dosage:

Hypertension: The usual starting dose is 10mg once daily, which may be adjusted by a doctor based on response.
Heart Failure: The starting dose is 2.5mg to 5mg once daily, with gradual increases.
Post-Heart Attack: A dose of 5mg within 24 hours of the attack, followed by maintenance dosing as prescribed.
Diabetic Nephropathy: Typically 10mg to 20mg once daily.

Important Notes:

Take Zestril 10mg Tablet at the same time each day with or without food.
Do not skip doses or stop taking the medication without consulting a doctor.
Drink plenty of water while on this medication to stay hydrated.

Side Effects of Zestril 10mg Tablet

Although Zestril 10mg Tablet is generally well-tolerated, some patients may experience mild to moderate side effects. Common side effects include:

Dizziness or Lightheadedness – This usually occurs when standing up suddenly.
Cough – A persistent dry cough is a common side effect of ACE inhibitors.
Fatigue – Some users may feel tired or lethargic.
Headache – Mild headaches may occur initially.
Nausea or Vomiting – Some individuals may experience digestive discomfort.

Serious Side Effects (Seek Immediate Medical Help)

Severe Allergic Reactions: Swelling of the face, lips, or throat.
Severe Dizziness or Fainting: This could indicate a sharp drop in blood pressure.
High Potassium Levels: Symptoms include muscle weakness and irregular heartbeat.
Kidney Issues: Reduced urination or swelling in the legs and ankles.

If you experience any severe side effects, stop taking the medication and seek medical attention immediately.

Precautions and Warnings

Pregnancy and Breastfeeding: Not recommended for pregnant or breastfeeding women due to potential harm to the baby.
Kidney and Liver Disease: Patients with kidney or liver impairment should consult a doctor before use.
Diabetes: May interact with diabetes medications, affecting blood sugar levels.
Low Blood Pressure: Individuals with hypotension should take extra caution.
Dehydration: Drink enough water to avoid dehydration-related complications.

Drug Interactions – What to Avoid

Diuretics: These may cause excessive blood pressure lowering.
Potassium Supplements: Increases the risk of high potassium levels.
NSAIDs (Ibuprofen, Naproxen): Can reduce the effectiveness of Zestril.
Diabetes Medications: May affect blood sugar control.
Alcohol: This can increase dizziness and lower blood pressure further.

Always inform your doctor about any medications you are currently taking to avoid potential interactions.

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Conclusion

Zestril 10mg Tablet is an effective medication for managing high blood pressure, heart failure, and kidney protection in diabetics. It provides multiple health benefits but must be taken under medical supervision.

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